LSD VIAL FUNDAMENTALS EXPLAINED

While in the LSD-certain crystal structure, the aspect chain from the lid residue L209EL2 forms comprehensive hydrophobic contacts with each LSD and surrounding residues in TMs III, IV, and V (Figure 4C). If the lid moved apart to expose the binding pocket in simulation, various of such contacts broke. We Hence hypothesized that L209EL2 acts as a l